18.03.2024 – 1min The Power of The Hippocampus: Uncovered Stress-Induced Memory EnhancementsThe exciting study titled “Hippocampal Mechanisms Support Cortisol-Induced Memory Enhancements” Hippocampal Mechanisms Support Cortisol-Induced Memory Enhancements | Journal of Neuroscience (jneurosci.org) explores the intricate link between stress, memory, and the hippocampus and shows stress-induced memory enhancements. To unravel this paradox, researchers employed a unique combination of behavioral assays, high-resolution fMRI, and cortisol manipulation. The study delves deep into the neural mechanisms at play during stress-induced memory enhancements. Key finding: Stress has a powerful influence on episodic memory, often boosting the encoding of emotionally salient information. Intriguingly, hydrocortisone, a stress-related hormone, emerged as a key player. It not only promoted the encoding of positive, subjectively arousing associative memories, but also led to enhanced functional connectivity between hippocampal subregions.The mouse model can be very useful in evaluating episodic memory, offering valuable insights for neuroscientific research. In cognitive, emotional and social phenotyping of mice in an observer-independent setting Dere et al. Cognitive, emotional and social phenotyping of mice in an observer-independent setting – PubMed (nih.gov) introduces a phenotyping battery based on the IntelliCage for comprehensive standardized behavioral assessment. The test battery includes place and reversal learning, sucrose preference, episodic-like memory, behavioral extinction and negative emotional contrast effect, as well as pheromone-based social preference.Reach out to us to find the best solution for your research field info@tse-systems.com.More news A Visionary in Neuroscience: Dr. Diego Bohórquez on Healing the Brain Through the GutA Visionary in Neuroscience: Dr. Diego Bohórquez on Healing the Brain Through the Gut Learn more Delving Deeper: IntelliCage Fat Mouse Corner and its Impact on Obesity ResearchObesity, a global health concern, presents a significant risk factor for cognitive decline and neurodegenerative diseases. Preclinical research utilizing obese mouse models plays a crucial... Learn more Young Blood May Hold the Key to Reversing AgingThe relentless march of time brings with it a gradual decline in cellular function. This process, known as aging, disrupts the delicate balance within our... Learn more Exploring Cognitive Aging: Insights from different Studies in Rodent Models Using the IntelliCage SystemLife expectancy has increased greatly over the last decades, but it has been associated with a progressive rise in the incidence of age-related diseases, including... Learn more Unlocking the Secrets of Gut Microbiota and Host Energy Metabolism: A Novel Approach with PhenoMaster-based Isolator SystemThe gut microbiota plays a vital role in regulating the host’s energy metabolism. Until recently, studies have shown that mice without microbiota accumulate less fat... Learn more Why MotoRater is the best choice for advanced kinematic gait analysisRodent (rats and mice) kinematic gait analysis is a fundamental approach to exhibit genomic and neuro-de/re-generative preclinical research. Recent advancements in technologies and analytic tools... Learn more
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Exploring Cognitive Aging: Insights from different Studies in Rodent Models Using the IntelliCage SystemLife expectancy has increased greatly over the last decades, but it has been associated with a progressive rise in the incidence of age-related diseases, including... Learn more
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Why MotoRater is the best choice for advanced kinematic gait analysisRodent (rats and mice) kinematic gait analysis is a fundamental approach to exhibit genomic and neuro-de/re-generative preclinical research. Recent advancements in technologies and analytic tools... Learn more