TraffiCage

Automated Assessment of Individual Locomotor Activity in Group Housed Mice or Rats

TraffiCage TSE Systems

Automated Locomotor Activity Monitoring

TraffiCage addresses a critical limitation in behavioral phenotyping – the reliance on solitary housing, which disrupts natural social interactions. This innovative system overcomes this challenge by enabling concurrent social housing and automated locomotor activity tracking via radio-frequency identification (RFID) technology.

TraffiCage empowers researchers to:

  • Follow Social Activity Connections: Investigate how social interactions influence individual locomotor activity patterns, offering insights into the social regulation of physical health.
  • Assess Social Impact on Disease Models: Evaluate the influence of social context on disease progression in rodent models, potentially leading to more generalizable preclinical data.
  • Refine Behavioral Phenotyping with Social Context: Improve our understanding of behavior by studying animals in a socially relevant environment that better reflects their natural habitat.

System Features

High throughput phenotyping screening

Assessment of circadian rhythms

Evaluation of social behavior

Detection of abnormal behaviors

Drug efficacy and toxicity screening

Locomotion Activity

Your Benefits

Rapid data generation

Tracking of locomotion in the animals’ home cage

Highest animal welfare

Continuous 24/7 recording of movements

Small footprint due to the placement beneath the cage

Data Acquisition and Analysis

The TraffiCage software offers efficient data handling capabilities:

  • Flexible Data Visualization: View individual animal data or user-defined group averages, facilitating tailored analysis based on research needs.
  • Seamless Data Export: All data is automatically saved in a format compatible with standard statistical analysis software, ensuring smooth integration into your existing workflow.

Compatible with

Stellar Telemetry

Multichannel implantable telemetry for In-vivo monitoring of physiological parameters.

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PhenoWorld

Unique and customized automated phenotyping solution for mice or rats.

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PhenoMaster

Metabolic cage system for mouse, rat or larger animals. Suitable for calorimetry, behavioral and physiological studies.

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Publications

Kotańska M, Dziubina A, Szafarz M, Mika K, Reguła K, Bednarski M, Zygmunt M, Drabczyńska A, Sapa J, Kieć-Kononowicz K. KD-64-A new selective A2A adenosine receptor antagonist has anti-inflammatory activity but contrary to the non-selective antagonist-Caffeine does not reduce diet-induced obesity in mice. PLoS One 2020; 15(6).

Kotańska M, Mika K, Reguła K, Szczepańska K, Szafarz M, Bednarski M, Olejarz-Maciej A, Nowak K, Latacz G, Mogilski S, Kuder KJ, Kieć-Kononowicz K, Sapa J. KSK19 – Novel histamine H3 receptor ligand reduces body weight in diet induced obese mice. Biochem Pharmacol. 2019; 168:193-203.

Lubelska A, Latacz G, Jastrzębska-Więsek M, Kotańska M, Kurczab R, Partyka A, Marć MA, Wilczyńska D, Doroz-Płonka A, Łażewska D, Wesołowska A, Kieć-Kononowicz K, Handzlik J. Are the Hydantoin-1,3,5-triazine 5-HT6R Ligands a Hope to a Find New Procognitive and Anti-Obesity Drug? Considerations Based on Primary In Vivo Assays and ADME-Tox Profile In Vitro. Molecules 2019; 24(24).

Partyka A, Zagórska A, Kotańska M, Walczak M, Jastrzębska-Więsek M, Knutelska J, Bednarski M, Głuch-Lutwin M, Mordyl B, Janiszewska P, Wesołowska A. Antidepressant-like activity and safety profile evaluation of 1H-imidazo[2,1-f purine-2,4(3H,8H)-dione derivatives as 5-HT1A receptor partial agonists. PLoS One 2020; 15(8).